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KMID : 0360220100510060912
Journal of the Korean Ophthalmological Society
2010 Volume.51 No. 6 p.912 ~ p.918
Trabeculectomy With Biodegradable Collagen Material: A Report of Two Cases
Hong So-Jin

Lee Jong-Rak
Choi Jin-Young
Choi Jae-Wan
Kim Yeon-Deok
Abstract
Purpose: To report two cases of trabeculectomy with biodegradable collagen material conducted on two post-vitrectomy patients.

Case Summary: The first patient was a 43-year-old woman with uncontrolled increased intraocular pressure (IOP) after pars plana vitrectomy with scleral buckling for diabetic retinopathy and vitreous hemorrhage. Another patient, a 28-year-old woman with aphakia, also had uncontrolled increased IOP after pars plana vitrectomy with encircling scleral buckling for retinal detachment. For both of these patients, we performed trabeculectomy using mitomycin C and recently developed biodegradable collagen matrix. In the first case, the IOP was increased three months after the surgery, for which needling was done. After needling, the IOP was well controlled in the range of 16 to 19 mmHg up to eight months postoperatively with stilling anti-glaucomatous eyedrops (Cosopt¨Þ, Xalatan¨Þ). In the second case, IOPwas increased one week after the surgery, but it was well controlled between 14 to 21 mmHg up to nine months postoperatively with anti-glaucomatous eye drops (Combigan¨Þ).

Conclusions: Biodegradable collagen matrix can possibly reduce the surgical failure of trabeculectomy and it is especially suitable for high risk patients when combined with anti-metabolic agents like MMC.
KEYWORD
Adjuvant therapy, Biodegradable, Collagen, Trabeculectomy, Wound healing
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